457 papers
This study demonstrates that predation by the nematode *Pristionchus pacificus* drives the evolution of *Myxococcus xanthus* aggregative multicellularity, revealing complex inter-trophic interactions and strong historical contingency influenced by antibiotic resistance.
This study identifies 21 evolutionarily conserved "lonely genes" located within massive, ancient gene deserts that predominantly encode cell adhesion molecules, revealing that their unique nuclear positioning at the lamina creates a regulatory vulnerability where dependence on specific chromatin modifiers for expression contributes to neurodevelopmental disorders.
This study utilizes simulations to demonstrate that population genomic statistics, particularly Tajima's D and segregating sites, are effective tools for detecting mosquito population declines in cluster randomized control trials, recommending a design of 3 to 5 villages per arm to achieve adequate statistical power for monitoring genetic biocontrol interventions.
By integrating genomic and morphological data from over 360 specimens, this study reveals that generalist habitat use and intermediate morphologies facilitated the rapid diversification of Australian dragon lizards from an ancestral arboreal state into specialized adaptive peaks.
This study utilized a novel approach of analyzing maternally inherited haploid megagametophyte tissue to resolve parental alleles in Scots pine embryos for investigating genomic imprinting, but found no evidence of imprinting, suggesting it may be absent or undetectable in conifers with the current methodology.
This study utilizes time-series analysis of a European maize landrace undergoing three cycles of selection to demonstrate that rapid trait improvement is driven by both the parallel fixation of major beneficial alleles and a polygenic response, effectively identifying candidate loci and genome-wide dynamics of selection.
By generating transcriptomes for six *Prophysaon* species, this study resolves previously unclear phylogenetic relationships, reveals undescribed diversity within the *P. andersonii-P. foliolatum* complex, suggests a role for introgression in their evolution, and proposes synonymizing the subgenus *Mimetarion* with *Prophysaon*.
This study provides the first empirical support for the sight-line hypothesis by demonstrating through macroevolutionary analyses of terns and allies that conspicuous eyelines evolve in association with foraging behaviors requiring accurate aiming, with specific eyeline angles aligning with the direction of travel in skimming species.
By applying a uniform annotation framework to nearly 500 beetle genomes, this study reveals that genome size and specific repetitive elements, particularly LINEs and LTR retrotransposons, are key predictors of gene family expansion, driving ecologically vital adaptations like chemosensory perception and detoxification.
By analyzing genome-wide data from 2,520 individuals across 18 reef taxa and 173 reefs globally between 1998 and 2018, this study reveals that while overall genetic distances remained stable, within-reef diversity is declining in key regions due to environmental stressors like rising temperatures, oxygen loss, and increased nitrates, which can be monitored via Earth observation to provide early warnings for genetic erosion.
This study presents the first evolutionarily standardized analysis of temporal niche diversification across nearly 20,000 tetrapod species, revealing that lineages have frequently shifted toward diurnality since the K-Pg extinction and that amphibians exhibit faster, more flexible temporal niche evolution than amniotes, highlighting the day-night cycle as a critical, independent yet interacting dimension of ecological opportunity alongside geographic space.
This study reveals that while mean protein length plateaus early in eukaryotic evolution, the mean exon count per gene continues to increase before saturating at approximately ten, identifying exon-intron architecture as a distinct and critical dimension of genomic complexity driven by minimal exon length constraints.
This paper proposes a framework integrating pharmacodynamics and population genetics to explain the non-repeatable and unidirectional patterns of collateral effects observed during drug resistance evolution, demonstrating how drug concentration and selection regimes critically influence these evolutionary outcomes.
This paper establishes a positive triangular invariant-set framework for evolutionary therapy that derives sufficient conditions for treatment-induced containment of drug resistance, demonstrating robustness against mutations and identifying explicit thresholds where therapy cycling can prevent evolutionary escape.
This study reveals that natural variation in the mouth-form plasticity of *Pristionchus pacificus* is regulated by plasticity in nonsense-mediated decay and alternative translation initiation, which generate distinct N-terminal proteoforms of the developmental switch gene *eud-1* and drive ecological shifts in population trait expression.
This study reveals that the high hatching failure rates in the near-extinct Hawaiian crow ('Alalā) are primarily driven by two specific recessive lethal haplotypes that persisted at high frequencies due to a severe population bottleneck, rather than by general genomic inbreeding levels.
This study reconstructs the fossilized brain of the Cambrian artiopod *Xandarella spectaculum*, revealing a unique neural organization with an expanded prosocerebrum and truncated protocerebrum that demonstrates clade-specific modifications to the ancestral euarthropod cerebral ground pattern.
This study integrates genomic data and ecological niche modeling to demonstrate that historical climate cycles drove the demographic bottlenecks, expansions, and genetic divergence of cactus wrens across North American deserts, ultimately leading to the speciation of *Campylorhynchus brunneicapillus* and *C. affinis*.
This study analyzes archaeological dental enamel proteomes to characterize the effects of in vivo amelogenesis-related protein cleavage and phosphorylation, ultimately proposing a novel phosphorylation-based marker for genetic sex estimation in human evolutionary research.
WINDEX is a novel hierarchical method that integrates site- and window-based statistics to more accurately detect and localize adaptive mutations and estimate the proportion of genomes under positive selection compared to existing approaches.